health – Naturally Inspiring

November 13, 2024

Is There an Association between Bacteria and Cancer?

Background

Pancreatic cancer is very deadly, with low survival rates, largely attributed to the fact that it does not present clearly with symptoms until it has reached a more serious stage (Kamisawa et al., 2016). In fact, out of the top 10 cancer-related deaths, pancreatic cancer is ranked number 7 (Khalaf et al., 2021). The pancreas is located near the liver, spleen, and gallbladder; within the abdomen (Fig. 1 Cleveland clinic diagram). It aids in digestion as well as the release of certain hormones. Pancreatic tumors can grow and obstruct the path of bile through the common duct, resulting in jaundice (Puckett, 2024), therefore not only interfering with the aforementioned pancreatic functions, but those of the organs around it. According to the Mayo Clinic, some common symptoms of pancreatic cancer include weight loss, jaundice, back pain, and blood clots.

November 4, 2024December 2, 2024

New study shows probiotics may help treat colon cancer

SEBASTIAN KAULITZKI/SCIENCE PHOTO LIBRARY/GETTY IMAGES

Background

Recently there has been a trend in increasing health and a significant portion of this has been tied to gut health. When it comes to gut health the gut microbiome is typically one of the first topics brought up; along with this comes the topic of maintaining and improving the bacteria in our gut. This is done in two fashions: diets and supplements. Within supplements, the ever more popular probiotics play an extremely important role in our gut health. Not only are probiotics beneficial in aiding digestion and other dietary benefits, but a recent study has shown that they may even suppress the formation of tumors, reduce colon inflammation, and cause the death of tumor cells related to colorectal cancer (CRC) (Zhou et al, 2024).

Colorectal cancer is the second most deadly cancer worldwide and it is occurring at an increasing rate, therefore it is of great importance that we continue to research the disease and find treatment options that may increase the outcomes for patients diagnosed with the disease (Patel et al, 2022). It is known that CRC patients may have altered gut microbiomes and that it may play a role in some of the symptoms of the disease as well as its progression (Cheng et al, 2020)(Yu et al, 2023). It’s also known that some probiotics can help restore a healthy balance of bacteria in the gut but can also reduce some of the harmful molecules that are produced by CRC (Amara et al, 2015)(Bender et al , 2023).

November 4, 2024

Fibromyalgia: a Mystery Disease?

What is Fibromyalgia and who does it affect?

Could you imagine waking up every day with pain that never goes away? That is the reality many fibromyalgia sufferers experience in their everyday lives. Fibromyalgia is from the Latin word fiber (fiber) and the Greek words myo (muscle) and algos (pain). These root words offer a glimpse into what fibromyalgia is and how it causes suffering. It is a pain of the fibrous tissues and muscle in the human body. While anyone of any background regardless of race or ethnicity can get fibromyalgia, it typically affects women more than men (NIH, 2024). You are more likely to develop fibromyalgia as you age, and if a family member has fibromyalgia. There are cases of children and young adults having fibromyalgia, but it usually occurs in middle-aged women (Erdrich et al., 2023).

Around 2 to 4% of adults live with the challenges of fibromyalgia (Stewart, 2022). They wake up, feeling exhausted, struggling to get through daily tasks, and facing unpredictable flare-ups. This chronic condition, along with many other symptoms mentioned can affect your mental health, sleep and cognitive issues like brain fog, chronic headaches, and memory impairment. In addition, It can also make you more at risk for depression and anxiety by more than 50% (Freirich et al., 2021). Figure 1(A) displays many of the possible or common symptoms that sufferers of fibromyalgia have. The National Institute of Health has a great page about fibromyalgia, including its symptoms, causes and an overview.

November 4, 2024

Heart Health in Your Gut: How the Microbiome Affects Cardiovascular Disease

When we think about heart health, the gut probably isn’t the first thing that comes to mind. However, new research is shedding light on how the trillions of microorganisms living in our digestive tract—collectively known as the gut microbiome—may play a surprising role in cardiovascular disease (Zhang, Y. et al., 2022).

Cardiovascular Disease: The World’s Deadliest Threat

Cardiovascular disease (CVD), is an umbrella term for conditions affecting the heart and blood vessels, including coronary artery disease (CAD), stroke and high blood pressure. These conditions are the leading cause of death worldwide, with heart attack and stroke being responsible for 85% of these deaths (World Health Organization, 2021). While many factors contribute to CVD, including diet, lifestyle, and genetics, scientists are discovering that the composition of our gut microbiome might also be a key player (Zhang, Y. et al., 2022).

October 21, 2021

Are Pet Owners’ Microbiome Unique?

A Brief Background:

Microbes found in our body and gut are responsible for many different functions of everyday life. Specifically, the human microbiome has prominent influences on health and disease (Kates et al., 2020). Have you ever questioned what can contribute to changes in our microbiome? The microbiome is defined as the community of microorganisms such as bacteria or fungi in a specific environment (Ursell et al., 2012). Although microbial changes are being considered in diet trends, probiotics, and environmental factors, pet ownership is often overlooked. Today, approximately 67% of U.S. households own a pet (APPA, 2021). Pet ownership brings us to the question, how may our microbiomes be impacted by pets living in our households? Many cats and dogs have similar microbiota compared to humans (Honneffer et al., 2014). Human-pet relationships can bring to light many pros and cons within our health. Many animals, especially those that roam outside, tend to bring in bacteria from the environment. This bacteria can then be easily transmitted (Resnick, 2012) to those living in the house, whether it’s via furniture, snuggling with your pet, or even something we consider harmless, like kissing your pet. Not only that, but bacteria such as Salmonella, E. coli, Clostridia, and Campylobacter are transmitted via pets and cause severe intestinal diseases for humans.

October 22, 2020October 23, 2020

From Microplastics to Microorganisms

Background

Over the last decade, plastic has become a more and more concerning source of pollution. In 2013 alone, almost 300 million pounds of plastic were produced worldwide (Lu et al 2017). Microplastics are defined as any plastic particle smaller than 5mm in diameter. Microplastics have been well documented as health concerns for marine life as more plastic accumulates in the ocean than any other place on earth. Additionally, microplastics have been found in a variety of household products including toothpaste and cosmetic products. We are just beginning to understand the extent microplastics have infiltrated our environment as well as our bodies, let alone the health risks they pose. One area of study deserving attention is the effect these plastics have on the microbiome of an organism. A microbiome is all of the bacteria, fungi, and viruses that live within or on a specific organism. Some of these microorganisms provide essential services to their host and maintaining a healthy microbiome has been tied to overall organismal health. Past studies have linked altered microbiomes to everything from obesity (Ridura et al 2013) to asthma (Stein et al 2016). Continue reading “From Microplastics to Microorganisms”

November 2, 2018

For the microbiomes of our future

Picture of a baby with bacteria visualized on it. — University of Utah (Learn Genetics)

The vaginal microbiome: We live in a world of microbes, and yet we are still learning new things about these millions of ‘germs’ every day and how they influence us, but what about our children? New research suggests a mother’s stress during pregnancy could be another puzzle piece in the development of baby’s microbiome and brain. According to the CDC nearly 4 million children were born in the United States in 2016, which resulted in mothers giving their offspring microbes, whether the baby was born through c-section or vaginally. Recent research (Rutayisire et al., 2016) is starting to show that there may be an advantage to birthing vaginally, as young are exposed to their mother’s microbiome. Continue reading “For the microbiomes of our future”

November 2, 2017November 2, 2017

Association Between The Human Microbiota and Type II Diabetes Mellitus

Microbes in a gut under magnifying glass (from www.diabetesdaily.com 2016)

Type II diabetes mellitus is increasing at an alarming rate, especially in children. According to the World Health Organization (WHO) statistics, the number of individuals with type II diabetes is projected to rise to more than 590 million by the year 2035 (Diabetes, 2017 and Upadhyaya, 2015). Type II diabetes is the result of the body’s resistance to insulin, a hormone that regulates blood sugar. The WHO states that type II is largely the effect of being overweight and very little exercise. Type I diabetes is distinguished by the bodies inability to produce insulin and there is no way to prevent it. Symptoms of type II diabetes include thirst, constant hunger, weight loss, vision loss, numbness in feet, and tiredness (Diabetes, 2017). Scientists are trying to discover new ways to mediate the effects of type II diabetes and many think that the gut microbiota of the human body might correlate with diabetes in an interesting way. Continue reading “Association Between The Human Microbiota and Type II Diabetes Mellitus”

November 22, 2016November 22, 2016

Could the Amish have it Right?

Asthma can be regulated by microbes. — Asthma can be regulated by microbes (credit: t3.ftcdn.net ).

Background: Can leading a simple traditional life correlate to health in non intuitive ways such as acting as a buffer against the development of asthma? Recent studies have shown that asthma is less prominent when microbial diversity is high (Genuneit, 2012); this trend has been observed in children involved in farming (Mutius,2010). Genuneit demonstrate that children who are exposed to farming have a 25% decreased chance of experiencing asthma (Genuneit, 2012). Logically it is sensible that the diversity of microbes would be higher in children exposed to farming, with all the dirt, hay and animals that comes with it, than children who are not exposed to that environment and live in more consistent sanitary lifestyle. In other words the diversity of a bacterial community across subjects (farm children vs. non-farm children) is much higher in children exposed to farming than those who were not. But how is such a phenomenon achieved? Continue reading “Could the Amish have it Right?”