Mental health diseases like depression and anxiety have plagued humans presumably since we achieved sentience, and lately it seems like the mental health crisis in America is getting worse and worse. Everyone blames this rise on something different; social media, the pandemic, tumultuous politics, or just the dramatics of younger generations. No matter where the blame is placed, statistics show that the rise in the number of diagnoses is real. Almost all mental health diseases show growth, but anxiety and depression have skyrocketed (ADAA). Even before the COVID 19 pandemic, anxiety was at an all time high, as shown in the figure below.
Depression is a mood disorder that is heterogeneous in nature. Depression causes severe symptoms that affect how a person feels, thinks, and handles daily activities (NIMH, 2017). According to the World Health Organization, depression affects over 300 million people and is a major worldwide contributor to the burden of diseases. This is especially pertinent considering that depression is one of the mood disorders associated with suicide, some others being anxiety, schizophrenia and PTSD. On an annual basis suicide leads to the death of nearly 800,000 people and is the second leading cause of death within the age group of 15 to 29 year olds (WHO, 2017). The underlying causes of depression are a complex interaction of social, psychological, and biological factors. It is essential to analyze these factors to understand the contribution of each in the development and maintenance of major depressive disorders. Continue reading “Depression and Microbial Dysfunction: A Link Between Gut Microbiota and the Brain.”
When studying mental illness, the brain has long been the focal organ of interest. Psychiatry and neurobiology examine communication from the brain and how its chemical imbalance produces central nervous system (CNS) disorders such as depression and anxiety. However, microbiology presents a new avenue of inquiry that is looking from the opposite direction: how is communication to the brain affecting mental health? This is a provocative question under investigation through recent studies of the microbiota of our gut.Continue reading “Does your gut control your brain?”