Make More Friends: It’s Good For Your Gut

It is currently estimated that the number of bacterial cells in our body roughly matches or exceeds the number of human cells, with the majority of these bacteria residing in the gut (Sender, et. al 2016). You may be familiar with literature identifying a “gut-brain” axis, i.e. a relationship between mental health and the composition of our microbiota. Studies have shown correlations between bacterial community makeup and disorders such as autism, depression and schizophrenia (Foster & Neufield 2013), (Dickerson, et. al 2017). Bacterial disbalance has also been correlated with diseases such as diabetes and obesity (Hartstra, et. al. 2014). A common factor between these disorders is that they are generally associated with lower microbial diversity.  While there is a growing body of literature supporting the relationships between disease and dysbiosis, a perturbation of the microbial community, little research has explored the relationships between personality and patterns in variation of the healthy microbiome.

Artwork by Anna & Ellen Balbusso

Enter Dr. Katrina Johnson of Oxford, who is especially interested in understanding how microbiota help to create the spectrum of human personality in the general population. To measure variation in personality, Johnson uses the “The Big Five” inventory which measures variation in personality using the following measures:  Continue reading “Make More Friends: It’s Good For Your Gut”

Depression and Microbial Dysfunction: A Link Between Gut Microbiota and the Brain.

Background

Depression is a mood disorder that is heterogeneous in nature.  Depression  causes severe symptoms that affect how a person feels, thinks, and handles daily activities (NIMH, 2017).  According to the World Health Organization, depression affects over 300 million people and is a major worldwide contributor to the burden of diseases. This is especially pertinent considering that depression is one of the mood disorders associated with suicide, some others being anxiety, schizophrenia and PTSD.  On an annual basis suicide leads to the death of nearly 800,000 people and is the second leading cause of death within the age group of 15 to 29 year olds (WHO, 2017). The underlying causes of depression are a complex interaction of social, psychological, and biological factors. It is essential to analyze these factors to understand the contribution of each in the development and maintenance of major depressive disorders.   Continue reading “Depression and Microbial Dysfunction: A Link Between Gut Microbiota and the Brain.”