In the 1940s Sir Alexander Fleming released the antibiotic Penicillin to the public transforming modern medicine forever. The emergence of antibiotics has had a profound impact on our lives, helping to increase our average life span from 56 to nearly 80 years (Ventola 2015). Antibiotics are an effective tool in fighting infection and have greatly reduced surgical complications. However, the flurry of excitement around these wonder drugs quickly went away. It was realized that the very microbes these drugs were supposed to be fighting were actually making them stronger and eventually became resistant to them. Continue reading “The Selflessness of Bacteria is Making Our Drugs Less Effective”
“Dad, you have to try it, don’t you?” Mary insists again.
Enrique doesn’t answer his daughter. What she’s implying will make him spend even more time in the hospital, to help someone in the distant future whom he will never meet, maybe. When he was 70, Enrique was diagnosed with acute myeloid leukemia (AML). As he understands it, some of his blood cells will never mature and perform the correct functions in his body. This cancer can be cured through chemotherapy in 25% of cases, but in most cases cannot be treated or reversed (Kornblau 2014). Enrique is contemplating joining a drug trial. In any given trial there is only a 10% chance that a patient will respond to the specific drug tested (Kornblau 2014). Some therapeutic drugs work for some patients, but how to match a patient to a drug is unknown; this is what the study Enrique might join is trying to figure out. Continue reading “The Chronicles of Evolutionary Weight in the Fight Against Cancer”