Guts, Genes, and Generations: Exploring Stress in the Microbiome

If you’ve ever met a set of identical twins, your initial impressions are likely about their similarities. Their height, facial features, and sometimes their mannerisms look like a reflection of the other. Visual similarities in identical twins can be traced back to genetics. When two people share the exact same set of DNA, their genes encode the same physical characteristics. But take a closer look, and you might notice that twins are not exactly the same. For example, their weight and skin texture may be different. One might develop a disease like cancer that the other never will. This discrepancy can be explained by environmental factors. Environment plays a huge role in shaping a person’s life. It can even affect how somebody’s genes work without ever changing their DNA (Peixoto et. al 2020). The study of the environment’s effect on genes is called epigenetics. Epigenetic changes can be passed down from parent to child (Geraghty et. al 2016).

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New study shows probiotics may help treat colon cancer

Background

Recently there has been a trend in increasing health and a significant portion of this has been tied to gut health. When it comes to gut health the gut microbiome is typically one of the first topics brought up; along with this comes the topic of maintaining and improving the bacteria in our gut. This is done in two fashions: diets and supplements. Within supplements, the ever more popular probiotics play an extremely important role in our gut health. Not only are probiotics beneficial in aiding digestion and other dietary benefits, but a recent study has shown that they may even suppress the formation of tumors, reduce colon inflammation, and cause the death of tumor cells related to colorectal cancer (CRC) (Zhou et al, 2024).

Colorectal cancer is the second most deadly cancer worldwide and it is occurring at an increasing rate, therefore it is of great importance that we continue to research the disease and find treatment options that may increase the outcomes for patients diagnosed with the disease (Patel et al, 2022). It is known that CRC patients may have altered gut microbiomes and that it may play a role in some of the symptoms of the disease as well as its progression (Cheng et al, 2020)(Yu et al, 2023). It’s also known that some probiotics can help restore a healthy balance of bacteria in the gut but can also reduce some of the harmful molecules that are produced by CRC (Amara et al, 2015)(Bender et al , 2023).

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What’s in US Ambulances?

Background

Ambulances are in almost every city in the United States. Depending on the city and service, ambulances can go on over a dozen calls a day. With each call and patient, healthcare workers and ambulance surfaces are exposed to new organisms. EMS (Emergency Medical Services) providers are constantly treating and transporting patients with viral infections and bacterial infections, trauma patients with open wounds, and patients with weak immune systems, such as young children and elderly (Caroline, 2013). Depending on the service, certain ambulances might get a higher population of patients with weakened immune systems than others, or more patients that have spent prolonged periods of time in hospitals. Continue reading “What’s in US Ambulances?”